Myxoid neurofibroma: An unusual presentation

Mediastinal Myxoid Neurofibroma: Unusual Location of a Rare Disease

Myxoid neurofibroma (MN) is a benign tumor of the peripheral nerves arising from connective tissue cells. This is a rare tumor characterized by immunostaining for S-100 protein [1]. From its nervous origin, its topography is fairly diverse. The most common locations of the MN are the face, shoulders, arms, periungual and in the feet. Mediastinal location has not yet been described. Through obse...

Kimura’s Disease – An Unusual Presentation

Introduction: Kimura’s disease is a rare chronic inflammatory disease of unknown etiology, presenting as painless subcutaneous nodules with lymphadenopathy and peripheral eosinophilia, mainly disturbing the head and neck region. It mainly affects Asian males in their 2nd to 4th decade of life. One such case of Kimura’s disease, which is uncommon in Indian natives, is reported.   Case Report: A ...

Mycosis fungoides with an unusual clinicopathological presentation

It is a challenging task to diagnose mycosis fungoides (MF), a type of primary cutaneous lymphoma, in the early stages of its development, due to the unspecific presentations associated with the disease. Histopathology and immunohistochemistry conduce to a more definite diagnosis. Presence of atypical T-cells in epidermis and upper dermis is the most significant pathologic finding. Herein...

Subungual myxoid neurofibroma on the thumb.

Precocious Puberty: An Unusual Presentation of Hypothyroidism

Hypothyroidism is usually associated with delayed pubertal development but in rare occasions precocious puberty may ensue which is seen in cases of prolonged and untreated hypothyroidism. This is also called the Van Wyk Grumbach syndrome. Here we present 4 cases of precocious puberty due to hypothyroidism.